Enantioselective conjugate addition of 3-fluoro-oxindoles to vinyl sulfone: an organocatalytic access to chiral 3-fluoro-3-substituted oxindoles.
نویسندگان
چکیده
An organocatalytic conjugate addition of prochiral 3-fluorinated oxindoles to vinyl sulfones was described for the first time. In the presence of bifunctional tertiary amine-thiourea catalysts, 3-fluoro-3-substituted oxindole adducts were obtained in excellent yields and with high enantiomeric excesses.
منابع مشابه
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ورودعنوان ژورنال:
- Organic & biomolecular chemistry
دوره 11 32 شماره
صفحات -
تاریخ انتشار 2013